The AMA continues to monitor current research, news, state health department reports and other relevant information from national, state and local public health agencies, law enforcement, emergency medical services, hospitals, treatment centers, and medical journals. During 2025, national trends have included:
- Emerging substances of misuse.
- Positivity—but uncertainty—about decreasing rates of drug-related mortality.
- Naloxone saves lives.
- A focus on medications for opioid use disorder.
- Adequate pain care.
- Increasing evidence of harms related to cannabis.